A multispecies probiotic enhances antimicrobial activity in cirrhosis: A randomized, double blind placebo-controlled study
A Horvath, B Leber, B Schmerboeck, M Tawdrous, G Zettel, A Hartl, T Madl, S Stryeck, D Fuchs, S Lemsch, P Douschan, E Krones, W Spindelboeck, F Durchschein, F Rainer, G Zollner, RE Stauber, P Fickert, P Stiegler, V Stadlbauer · Zeitschrift für Gastroenterologie · 2016 · Heft 05
Bibliografische Angaben
Zusammenfassung
The innate immune system of cirrhotic patients is challenged by an increased level of gut derived bacterial products that enter the body through a leaky gut. Probiotics may correct gut permeability and have beneficial effects on host defence mechanisms. We consequently tested the effects of a multispecies probiotic on gut permeability, bacterial translocation and innate immune function in a randomized, double blind, placebo-controlled study. Therefore, stable cirrhotic patients (n = 44) received either a mixture of eight different probiotic strains (Ecologic® Barrier) or a placebo (n = 36) for six months and wer…
