Novel Immunomodulatory properties of Uva-ursi folium extract

Arctostaphylos uva-ursi folium (bearberry leaf) is traditionally used for the treatment of symptoms of mild recurrent lower urinary tract infections such as burning sensation during urination and/or frequent urination. In addition to the antibacterial activity, it has also been suggested that preparations of Uva-ursi folium possess anti-inflammatory beneficial properties. In the present study, we investigated the effects of an ethanolic Uva-ursi extract and the corresponding herbal medicinal product Cystinol® akut, on cytokine release in human primary peripheral monocytes. Uva-ursi extract and Cystinol® had no e…