Development and validation of a novel line immunoassay for diagnosis of Helicobacter pylori infection

Background: The infection with Helicobacter pylori (H. pylori) addects 50% percent of the world population. By colonizing the human stomach, the bacteria cause gastritis in all infected individuals. 10 – 15% of H. pylori positive individuals develop ulcer disease and 1 – 2% gastric cancer. Both, strain-specific virulence and host factors influence the course of disease. While timely eradication of the pathogen is the most effective way to prevent development of gastric cancer, it is uncertain which infected individuals are at risk and require treatment. Material/methods: The novel recomLine Helicobacter IgG, IgA…