Prediction of preeclampsia by maternal carotid intima-media-thickness, blood pressure, flow-mediated dilatation and uterine artery Doppler

Purpose: To evaluate the performance of a 1st, 2nd and 3 rd trimester (T) prediction model for preeclampsia (PMPE) by a combination of carotid intima media thickness (cIMT), flow-mediated dilatation (FMD), retinal arteriolar-venular ratio (AVR), mean arterial pressure (MAP), and uterine artery (UtA) Doppler. Methods: We performed the combined screening in 761 pregnant women, of whom 292 were analyzed in the 1st, 475 in the 2nd and 407 in the 3 rd trimester. cIMT and FMD were assessed using high-resolution ultrasound and an automated reading program and AVR was calculated using a specific retinal vessel analyser.…