Anti-Pseudomonas aeruginosa IgG Antibodies and Chronic Airway Infection in Non-Cystic Fibrosis Bronchiectasis
G Suarez-Cuartin, O Sibila, A Smith, H Abo-Leyah, A Rodrigo-Troyano, S Vidal, V Plaza, TC Fardon, JD Chalmers · Pneumologie · 2016 · Heft 10
Bibliografische Angaben
Zusammenfassung
Rationale: Identification of Pseudomonas aeuginosa (PA) infection status is important in the management of non-cystic fibrosis bronchiectasis. Serum anti-PA IgG antibodies have been proposed to diagnose chronic PA infection. Methods: Clinically stable bronchiectasis patients were studied prospectively. Chronic PA infection was defined as 2 or more positive sputum samples at least 3 months apart and/or failure to clear PA following eradication treatment. Baseline serum samples were assayed for anti-PA IgG by a validated ELISA kit. The cut-off value for a positive ELISA Unit/10 result was 2.96. Results: 361 patien…
