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Neutrophil-lymphocyte ratio: an independent predictor of the herpes zoster risk in rheumatoid arthritis patients treated with tofacitinib

Pengcheng Liu, Min Zhang, Yueqin Zhang, Shujiao Yu, Rui Wu · Aktuelle Rheumatologie · 2025 · Heft 02 · S. 134-140

Dokument
937677
CareLit-ID
Jahr
2025
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Aktuelle Rheumatologie
Autor:innen
Pengcheng Liu, Min Zhang, Yueqin Zhang, Shujiao Yu, Rui Wu
Ausgabe
Heft 02 / 2025
Jahrgang 50
Seiten
134-140
Erschienen: 2025-04-01 00:00:00
ISSN
0341-051X

Zusammenfassung

AbstractTo investigate the role of the neutrophil-lymphocyte ratio (NLR) in the risk of developing herpes zoster (HZ) in patients with rheumatoid arthritis (RA) receiving tofacitinib. This was a prospective observational study recruiting patients who were diagnosed with RA and treated with tofacitinib. Patients with previous herpes zoster infections were excluded from this study. All patients were assessed for HZ every 1–3 months and were followed up for 12 months. Univariate and multivariate logistic regression analyses were used to assess the relationship between NLR and HZ. A cutoff value of NLR was determine…

Schlagworte

herpes zoster rheumatoid arthritis tofacitinib biomarker neutrophil-lymphocyte ratio rheumatoide Arthritis Neutrophil-Lymphozyten-Verhältnis Aktuelle Rheumatologie