CareLit Fachartikel

Purification and Characterization of Urinary Stone Protein

K. Kohri, K. Fujita, T. Itoh, T. Tawada, T. Sakakura, T. Umekawa, T. Kurita · Aktuelle Urologie · 1996 · Heft S 1 · S. 27-29

Dokument
958009
CareLit-ID
Jahr
1996
Publikation
PDF
nein
Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Aktuelle Urologie
Autor:innen
K. Kohri, K. Fujita, T. Itoh, T. Tawada, T. Sakakura, T. Umekawa, T. Kurita
Ausgabe
Heft S 1 / 1996
Jahrgang 27
Seiten
27-29
Erschienen: 1996-04-01 00:00:00
ISSN
0001-7868
DOI
10.1055/s-2008-1055643

Zusammenfassung

Summary: The character and role of the urinary stone matrix is poorly understood. Our recent study revealed that the cDNA sequence of osteopontin encodes the urinary stone protein. We now present the results of our further study on osteopontin as well as the identification of another stone matrix protein; calprotectin. Calprotectin was extracted from calcium oxalate stone protein with EDTA. The molecular weight was 41.5 kDa. The expression of calprotectin was observed in distal tubular cells and its surrounding connective tissue like osteopontin. This study shows that both osteopontin and calprotectin in the kid…

Schlagworte

Osteopontin Stone matrix Calprotectin Calcium oxalate Urinary stone Aktuelle Urologie