The economic impact of treatment management strategies in antiviral therapy of chronic hepatitis C
U Siebert, G Sroczynski, J Wasem, P Aidelsburger, JB Wong, S Rossol · Zeitschrift für Gastroenterologie · 2015 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction: Chronic hepatitis C causes significant morbidity and mortality in Germany. Cost estimates for antiviral therapy for chronic hepatitis C (CHC) often neglect dose reductions/discontinuations, clinical management algorithms, and future savings associated with the prevention of advanced liver disease. Objective: To assess the costs of antiviral treatment (AVT) and advanced liver disease for patients with chronic hepatitis C treated with peginterferon alfa-2b plus ribavirin considering clinical stoppage algorithms, discontinuations and dose reductions in the context of the German health care system. Met…