Stimmt es eigentlich, dass subkutanes Methotrexat der oralen Gabe hinsichtlich Wirksamkeit und Verträglichkeit bei der Behandlung der JIA überlegen ist?
Anna Raab, Frank Dressler, Ariane Klein · Kinder- und Jugendmedizin · 2025 · Heft 06 · S. 335-340
Bibliografische Angaben
Zusammenfassung
AbstractMethotrexate (MTX) is the most commonly prescribed conventional disease-modifying antirheumatic drug (DMARD). Numerous international guidelines for polyarticular juvenile idiopathic arthritis (pJIA) recommend MTX as a first-line therapy and basic medication, yet there is a lack of consensus-based recommendations on the form of administration. This is not standardized and depends on the preference of the treating rheumatologist 1, 2. Overall, there are only a few publications on the evidence regarding the method of application of MTX in JIA. The results are highly variable and contradictory, probably due…