MRS relaxometry and diffusion tensor imaging (DTI) at 3T in patients with idiopathic Parkinson disease
C Krautmacher, F Träber, P Mürtz, O Kanimogaddam, O Guer, W Block, U Wüllner, H Schild · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2004 · Heft 03
Bibliografische Angaben
Zusammenfassung
Purpose: DTI potentially uncovers structural changes in diseased substantia nigra. At 3T, DTI may be impaired by increased susceptibility. Shortened T2 relaxation times in basal ganglia could reflect increased iron content. Accuracy of MRS relaxometry may benefit from higher magnetic field (3T). This study was designed to test the feasibility of DTI at 3T and to search for differences between patients and controls by DTI and MRS relaxometry. Methods and Materials: We examined 12 patients with Parkinson disease and 13 healthy controls with MRS relaxometry and DTI at 3T, 11 controls were examined with DTI at 1.5T.…