Alterations of redox-homeostasis in bowel parts

Introduction: Unhealthy nutritional costumes could result in inflammatory processes and necrosis in the gastrointestinal tract in which free radical reactions are involved. Aim: Now, the question is, whether the lipid rich diet is able to influence on cellular redox state in all parts of gut in alimentary induced bowel disease. Methods: Twenty Wistar rats were divided into two groups: control and fat rich diet fed groups. Lipid rich diet (2% cholesterol 0.5% cholic acid, 20% sunflower oil added to the rat chow) was applied for 10 days. After exsanguinations in deep pentobarbital narcosis, bowel parts were isolat…