Visceral hypesthesia in patients with Crohn's disease

Visceral hyperesthesia was found to play etiologic role in the development of symptoms of irritable bowel syndrome (IBS). Crohn's disease (CD) was shown to produce chronic abdominal pain. The aim of our study was to test the perceptual thresholds to rectosigmoideal balloon distension in patients with CD. Rectosigmoideal balloon distension was carried out with semirandom ascending phasic (870ml/min) distension with SVS-barostat in 5 CD (without any inflammatory manifestations in the rectosigmoideal region), in 5 Rome II positive alternating IBS patients and in 5 healthy volunteers. Results: Pressures of urge were…