Coherence and Phase Coupling in the Scalp EEG and between LORETA Model Sources, and Microstates as Putative Mechanisms of Temporo-Spatial Functional Organization

What are the brain mechanisms that incorporate the seemingly homogeneous experience of a percept or a thought? Higher brain functions assumedly are generated by sets of neural sub-systems that are distributed in various brain regions and that are temporally coordinated. EEG and ERP measures of coherence or phase coupling aim at such functional temporal connections between regions. However, results obtained from scalp recorded electric data (including recomputations to CSD) are ambiguous concerning source localization because electric sources are oriented, and are not necessarily perpendicular to the head surface…