Topographic Plasticity of Language Sites across Time

Convincing evidence of individual variability in location of language exists from intraoperative cortical stimulation results during awake craniotomies in patients with lesions in eloquent areas. However, little information is available about whether the localization of these areas is stable over time or if plastic changes allow a topographic shift of the functional units in the adult brain. The purpose of this investigation was to find out whether the localization of language-associated areas in the inferior frontal gyrus was reproducible in a 23-year-old, right-handed man who presented with a history of febril…