Quantitative gene profiling in human adult neural stem cells

Recently we showed the successful isolation and expansion of neural stem cells from adult human brain (hbNSC for human brain-derived neural stem cells). Furthermore, we reported the conversion of adult human mesodermal stromal cells (hMSCs) into cell with all major properties of neural stem cells (hmNSC for human mesodermal-derived neural stem cells). Both types of NSCs can be easily expanded neither losing the markers typical for neural stem cells nor their differentiation potential. Here we report on quantitative gene expression analysis comparing haNSCs, hmNSCs, hMSCs and human adult cortical tissue using qua…