Auch bei niedrigem LDL-Cholesterin aggressiv therapieren - Aktueller Stellenwert der Statintherapie beim akuten Koronarsyndrom
W. März · Der Klinikarzt · 2005 · Heft 04 · S. 108-112
Bibliografische Angaben
Zusammenfassung
Zusammenfassung Lowering LDL cholesterol with statins is an empirically supported strategy to reduce the incidence rate of cardiovascular events and deaths in individuals at high cardiovascular risk and in patients with stable coronary artery disease. As aggressive lowering of LDL may have immediate effects on the function of the vascular system, the use of statins has recently been evaluated in patients with acute coronary syndromes. In the MIRACL study, treatment with 80 mg atorvastatin daily reduced the incidence rate of vascular events compared to placebo in patients with acute coronary syndrome. The PROVE-I…