Serum leptin, soluble leptin receptor levels and free leptin index in patients with primary biliary cirrhosis
F Szalay, T Csak, A Folhoffer, A Horvath, G Speer, Z Nagy, P Lakatos, A Habior, I Tornai, P Lakatos · Zeitschrift für Gastroenterologie · 2005 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background/Aim: The pathophysiology of osteoporosis (OP) in chronic liver diseases is unknown. Recent data suggest that serum leptin is associated to bone mineral density (BMD). In animal studies leptin was found to be a potent inhibitor of bone formation. Low and also high serum leptin level was reported in patients with chronic liver diseases. We aimed to investigate the relationship between serum leptin levels, free leptin index (FLI) and BMD in patients with primary biliary cirrhosis. Patients and methods: 94 patients with PBC (each female, AMA M2 positive, age: 59.1±SD8.8 year, mean BMI: 24.9±4.0kg/m2) and…
