TREATMENT OF SIALORRHOEA WITH ULTRASOUND-GUIDED BOTULINUM TOXIN INJECTION IN PATIENTS WITH PARKINSON'S DISEASE OR AMIOTROPHIC LATERAL SCLEROSIS

Purpose: Sialorrhoea is frequent in neurodegenerative diseases. Anticholinergic drugs, radiation and surgery over salivary glands or ducts have been used to reduce drooling. These treatments are often ineffective or associated with severe side-effects. Recently, injection in the salivary glands of botulinum toxin (BTX) A or B emerged as a promising alternative treatment. We evaluated its efficacy and tolerability by ultrasound-guided injection in the salivary glands in patients with sialorrhoea associated to Parkinson's disease (PD) or Amiotrophic Lateral Sclerosis (ALS). Methods and Materials: Sixteen patients…