Upbeat nystagmus as the initial clinical sign of Creutzfeldt-Jakob disease
M Strupp, V.C Zingler, K Jahn, M Glaser, H Kretzschmar, T Brandt · Aktuelle Neurologie · 2005 · Heft 10
Bibliografische Angaben
Zusammenfassung
Background: Ocular motor disorders (such as horizontal nystagmus, saccadic pursuit, gaze deviations, and pathological saccades) have been reported in patients with Creutzfeldt-Jakob disease (CJD). We report on a patient with autopsy-proven CJD who complained of dizziness and presented with upbeat nystagmus (UBN) as the initial clinical sign. Case report: The 68-year-old man was admitted with a one-week history of dizziness and unsteadiness. The neuro-ophthalmological examination revealed an upbeat nystagmus, associated with a diminished downward optokinetic nystagmus and a slightly saccadic pursuit. The subjecti…