CareLit Fachartikel
A Two Step Approach to Autologous Peripheral Blood Stem Cell Transplantation for Refractory Chronic Inflammatory Bowel Diseases – Results of a Pilot Study
K Potthoff, T Baumert, H Bertz, C Arnold, J Finke, W Kreisel · Zeitschrift für Gastroenterologie · 2006 · Heft 04
Dokument
965133
CareLit-ID
Jahr
2006
Publikation
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Metadaten
DOI
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zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: In about 5% chronic inflammatory bowel diseases (IBD) are refractory to current medical or surgical treatment. Ubiquitous bacterial antigens are supposed to trigger an uncontrolled immune reaction in IBD based on a genetic predisposition. Therefore it is intriguing to try to eliminate the disturbed immune reactions and to redevelop a better immunological tolerance. Methods: We used a two step approach towards autologous peripheral blood stem cell transplantation (aPBSCT) in patients with IBD refractory to corticosteroids, aminosalicylates, immunosuppressors, antibiotics and Infliximab. Remission is…
Schlagworte
Cyclophosphamide
After
Blood
Transplantation
Budesonide
Antigens
Zeitschrift für Gastroenterologie
