Expression of genes relevant for tumour aggressiveness in endometrial cancer
E Steiner, J Sagemüller, J Brieger, C Lindner, J Hengstler, M Schmidt, H Kölbl · Zentralblatt für Gynäkologie · 2005 · Heft 10
Bibliografische Angaben
Zusammenfassung
Objective: The aim of this study was, to analyse the expression of identified genes in endometrial cancer tissue, witch might be responsible for tumour aggressiveness. Methods: After identification and analysis of differential displayed cDNA in matched paired patients with endometrial cancer with and without metastatic recurrence, three cDNA samples (edi1, edi-2 and edi-3) were reamplified and sequenced. An NCBI-database request on homologies on these three sequences was done. To measure and to analyse the expression of these three cDNA samples TAGMAN-assay was used on 54 cases (42 without and 12 with recurrent…