Current results of pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy in patients with chronic hepatitis C

Introduction: Long-term treatment with PEG-IFNs combined with RBV is currently regarded as the best antiviral treatment for chronic hepatitis C (CHC). Aim: To survey our experience with this treatment modality. Patients and methods: Since January 2004, the 1-year treatment of 115 CHC pts has been started with once-weekly injections of PEG-IFN combined with 1.0–1.2g RBV daily. Ninety-eight had not participated in previous IFN treatment, 2 were relapsers to IFN monotherapy, 2 was a relapser to PEG-IFN monotherapy, and 13 had relapsed following previous standard IFN + RBV therapy. To date 110 pts have reached the 1…