Hypertonic-Hyperoncotic Solutions Improve Cardiac Function in Children after Open Heart Surgery

Objectives: Hypertonic-hyperoncotic solutions (HHS) are used for improvement of micro- and macrocirculation in various types of shock. In paediatric intensive care controlled, randomized studies with HHS are lacking. The aim of this randomized, double-blind study was to evaluate the hemodynamic effects of HHS in children. Methods and Measurements: 50 children were randomized after open heart surgery. Immediately after arrival on intensive care, HHS (7.2% NaCl, 6% hydroxyethyl-starch) or isotonic saline (ISS) was administered. Cardiac index (CI), stroke volume index (SVI), systemic vascular resistance index (SVRI…