A randomised pilot trial of visual restoration therapy

Background and purpose: Evidence from non-randomized studies suggest a beneficial effect of visual restoration therapy (VRT) in patients with retro-chiasmatic visual pathway lesions. We investigated the feasibility and effect of VRT in a prospective, single center, randomized pilot trial. Patients and methods: The 42 patients with chronic, stable visual field deficits (mean age 59, SD 12; 41% women; 95% stroke) were randomly asigned (3:1) to either VRT (6-months pc-based daily visual field training, n=34) or sham procedure (n=8). Outcome measures (compared to baseline at study inclusion) were: visual field stimu…