A quantitative systematic review of hyperbaric oxygen therapy for acute ischaemic stroke

Aims: It has been postulated that hyperbaric oxygen therapy (HBOT) may improve outcome in patients following acute ischaemic stroke. The aim of this review was to assess the effectiveness and safety of adjunctive HBOT in the treatment of acute ischaemic stroke. Methods: A systematic search for all randomized controlled trials that compared HBOT in the treatment for acute ischaemic stroke in comparison to a controll group (sham or placebo treatment) was performed (Cochrane Stroke Group Trials Register, Cochrane Central Register of controlled Trials, Medline, Embase, CINAHL, DORCTIHM, hand-search of journals and c…