Progressive multifocal leukoencephalopathy successfully treated with Cidofovir in a patient with pulmonary sarcoidosis

We report the clinical course of a 68 year-old patient who developed symptoms of the parieto-occipital cortex. Homonymous hemianopia and brachiofacial paresis on the right, mnestic aphasia and disturbances in reading, writing, and calculating were slowly progressive over 4 months. MRI scans of the brain were consistent with progressive multifocal leukoencephalopathy (PML), the diagnosis of which could be ensured by DNA of JC virus (JCV) in the cerebrospinal fluid (CSF) by polymerase chain reaction. In the medical history mild pulmonary sarcoidosis was known, but there was no need for treatment with immunosuppres…