Videoendoscopic and histopathologic assessment of columnar lined esophagus in patients with gastroesophageal reflux

Background and Aims: Controversy exists if biopsies should be obtained from an endoscopically normal appearing esophagogastric junction in patients with gastroesophageal reflux disease. We addressed this issue using video endoscopy and histopathology. Methods: 114 consecutive patients (58 males) with gastroesophageal reflux disease prospectively underwent endoscopy, including biopsy sampling from the esophagogastric junction. Endoscopy was digitally recorded and reviewed. Initial endoscopy report was compared to revised report following analysis of recording and correlated with histopathology. Results: In 65 pat…