Quantitative and qualitative MR imaging using Ultra short TE at 3T for image guided radioembolization of liver metastases

Purpose: Local radiation therapy with neutron-activated holmium-loaded microspheres (HoMS) is a novel and promising treatment technique for both unresectable liver metastases and hepatocellular carcinoma [1]. In embolization therapies with radioactive microspheres, accurate assessment and quantification of the biodistribution is of major importance for treatment planning, dosimetry and follow up [2]. Since holmium is strongly paramagnetic it can be used as a T2 * contrast agent [3]. In this work we utilize ultrashort TE (UTE) imaging in combination with multiple gradient echo (MGE) acquisition to allow the quant…