CareLit Fachartikel

Is the detection of microbial DNA superior to ascitic fluid bacterial culture in patients with suspected spontaneous bacterial peritonitis?

T Bruns, S Sachse, S Assefa, M Lehmann, A Herrmann, E Straube, A Stallmach · Zeitschrift für Gastroenterologie · 2009 · Heft 01

Dokument
968564
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
T Bruns, S Sachse, S Assefa, M Lehmann, A Herrmann, E Straube, A Stallmach
Ausgabe
Heft 01 / 2009
Seiten
–
Erschienen: 2009-01-20 00:00:00
ISSN
0044-2771
DOI
10.1055/s-0029-1191963

Zusammenfassung

Spontaneous bacterial peritonitis (SBP) is a common and often fatal complication in patients with advanced liver cirrhosis. It is defined by an elevated absolute polymorphonuclear leukocyte (PMN) count ≥ 250/mm³ and a positive ascitic fluid bacterial culture. With current bacterial culture techniques pathogenic agents are detected in only 50% to 80% of patients with neutrocytic ascites. Hence, faster and more sensitive methods for detection for bacteria in ascitic fluid are needed. In a prospective study 96 diagnostic paracenteses were performed on 62 patients with ascites who were admitted consecutively to our…

Schlagworte

CNNA SBP ascites bacterascites bacterial DNA cirrhosis diagnostic multiplex-PCR neutrocytic ascites translocation Zeitschrift für Gastroenterologie