Transcranial direct current stimulation in therapy-resistant depression: a double-blind, placebo-controlled study
U Palm, D Keeser, Z Fintescu, C Schiller, E Reisinger, C Mulert, O Pogarell, HJ Möller, F Padberg · Klinische Neurophysiologie · 2009 · Heft 03
Bibliografische Angaben
Zusammenfassung
Background: Direct current stimulation (DCS) for modulating membrane potentials is known since the 1960s. Recently, Transcranial direct current stimulation (tDCS) has been rediscovered in motor cortex neurophysiology and investigated as therapeutic intervention in neuropsychiatric disorders. Based on the role of the dorsolateral prefrontal cortex (DLPFC) in the pathophysiology of depression and previous studies with repetitive transcranial magnetic stimulation (rTMS) in depression, Fregni et al. investigated anodal tDCS of the left DLPFC in three consecutive trials yielding promising results. However, no data ar…
