Analysis of Serum-Free Culture of Umbilical Cord Blood-derived Endothelial Cells
SM Zeisberger, S Chen, M Riegel, S Zoller, A Sachinidis, AH Zisch · Zeitschrift für Geburtshilfe und Neonatologie · 2009 · Heft 04
Bibliografische Angaben
Zusammenfassung
The success of therapeutic vascularisation and tissue engineering will rely on our ability to create vascular networks using human endothelial cells (ECs) that can be obtained readily, can be expanded safely ex vivo, and can produce robust vasculogenic activity in vivo. The lack of sufficient vasculature for the supply with nutrients and oxygen is still a limiting factor for the successful implantation of tissue engineered constructs and leads in many cases to the failure of the implant. A strategy to improve vascularisation of bioengineered tissues might be the incorporation of or vascular-like structures in th…
