Liver failure occurring as part of systemic BCG sepsis

Introduction: Local BCG installation increases T-cell immunoresponse and therefore postoperative intravesical BCG installation is used to prevent the reoccurrence of bladder cancer. The treatment is well tolerated in 95% of the patients, 5% of them develop local and systemic symptoms, and in 0.5% of the cases a life threatening BCG sepsis occurs. Case study: A 63-year old man underwent laser therapy followed by local BCG installation due to bladder cancer. He was hospitalised after the 5th installation session with high fever. As thorough investigations could not detect any other possible cause, a systemic BCG r…