Somatosensory evoked potentials in epileptic children treated with carbamazepine or valproate in monotherapy

Introduction: Data from literature suggest that long-term therapy with various antiepileptic drugs can be responsible for the functional disturbances within nervous system e.g. peripheral neuropathy and encephalopathy. The useful and non-invasive instrument for evaluation of even subclinical nerve conduction abnormalities in somatosensory tracts is somatosensory evoked potentials study (SEP). Objective: Aim of the study was to assess potentially abnormalities in SEP parameters in epileptic children, treated chronically in monotherapy with one of the two most often used antiepileptic drugs: valproate (VPA) or car…