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Leukapheresis and Exchange Transfusion in Children with Acute Leukemia and Hyperleukocytosis. A Single Center Experience

R. Haase, N. Merkel, O. Diwan, K. Elsner, C. M. Kramm · Klinische Pädiatrie · 2009 · Heft 06 · S. 374-378

Dokument
969330
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Jahr
2009
Publikation
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Klinische Pädiatrie
Autor:innen
R. Haase, N. Merkel, O. Diwan, K. Elsner, C. M. Kramm
Ausgabe
Heft 06 / 2009
Jahrgang 221
Seiten
374-378
Erschienen: 2009-11-01 00:00:00
ISSN
0300-8630

Zusammenfassung

Abstract BACKGROUND: The risk of severe complications or death during the initial period of acute leukemia was markedly decreased due to the progress in pediatric oncology and use of simple measures like hyperhydration, forced diuresis, treatment of hyperuricemia, correction of electrolyte and coagulation disturbances and the careful use of antileukemic drugs. The incidence of leukostasis and tumor lysis syndrome depends on absolute initial white blood cell counts and the underlying type of leukemia. Leukapheresis or exchange transfusion may improve the prognosis of high risk patients. METHODS: Records of all pe…

Schlagworte

hyperleukocytosis leukapheresis exchange transfusion tumor lysis syndrome Hyperleukozytose Leukapherese Austauschtransfusion Leukostase Tumor-Lyse-Syndrom Klinische Pädiatrie