Comparison of two rapid bedside strip test for the detection of amniotic fluid

Objective: To compare two immunoassay rapid strip tests for the detection of amniotic fluid, ActimPROM Test® (Medix Biochemica, Finnland), based on the detection of insulin-like-growth-factor-binding-protein–1 (IGFBP–1), and AMNISure® (AMNISURE, Cambridge, MA, USA), based on the detection of placental α-microglobulin–1 (PAMG–1). Aims: Placental α-microglobulin–1 (PAMG–1), a 34-kd protein, has been detected in amniotic fluid and has therefore been taken as marker for a new beside test. Up to now, the standard method for rapid detection of amniotic fluid is based on the detection of IGFBP–1. Material and Methods:…