CareLit Fachartikel

The Story of Inhaled Insulin

JS Patton · Pneumologie · 2007 · Heft 02

Dokument
971585
CareLit-ID
Jahr
2007
Publikation
PDF
nein
Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
Pneumologie
Autor:innen
JS Patton
Ausgabe
Heft 02 / 2007
Seiten
–
Erschienen: 2007-02-15 00:00:00
ISSN
0934-8387

Zusammenfassung

Introduction The feasibility of inhaled insulin was demonstrated in diabetics in Germany in 1925 (1). But the efficiency was low (˜3%) and at the time, insulin was in very short supply. This early observation was forgotten and the feasibility of inhaled insulin was again demonstrated in humans in l971, but it was uncertain if the correct dose could be reliably given (2). Then in the 1980s a series of nebulization studies in humans further demonstrated the feasibility of inhaled insulin and showed that with appropriate devices, insulin could be inhaled reliably (3,4). Until l993, all studies were conducted with l…

Schlagworte

Absorption Blister Bronchioles Observation Caveolae Biology Bronchi Germany Blood Diet After Pneumologie