High prevalence of coeliac disease among first-degree relatives of coeliac patients in Hungary
M Juhász, K Csőkör, L Berczi, T Zágoni, H Székely, L Herszényi, I Pregun, Z Tulassay · Zeitschrift für Gastroenterologie · 2007 · Heft 05
Bibliografische Angaben
Zusammenfassung
Aims: The prevalence of coeliac disease (CD) among first-degree relatives (FDR) is estimated to be as high as 10%. Aim: To evaluate the prevalence of CD among FDRs in our patient cohort. Patients and methods: Since 1999, following the diagnosis of CD in an index patient, we have offered the FDRs serology screening (EMA and tTG). Positive serologies were confirmed by histology applying the modified Marsh criteria. Index patients represented all of the major geographic areas of Hungary. Results: During this period, we advised family screening to 72 coeliac patients, 25 of them (35%) agreed to bring a total of 54 F…
