Pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy in chronic hepatitis C: a single-center experience

Introduction: PEG-IFN combined with RBV is currently regarded as the best antiviral treatment for chronic hepatitis C (CHC). Aim: To survey our experience with this treatment modality. Patients and methods: The pts were treated for one year with once-weekly injections of PEG-IFN combined with 1.0–1.2g RBV daily. To date 111 of them have completed the course of therapy and the follow up period. Ninety-six had not participated in previous IFN treatment, 2 were relapsers to IFN monotherapy, 1 was a relapser to PEG-IFN monotherapy, and 12 had relapsed following previous standard IFN + RBV therapy. Results: Among the…