Serum Chromogranin A levels after administration of a single dose of proton-pump inhibitor
I Pregun, L Herszényi, M Juhász, P Miheller, G Nagy, G Lakatos, F Sipos, P Pusztai, K Rácz, Z Tulassay · Zeitschrift für Gastroenterologie · 2007 · Heft 05
Bibliografische Angaben
Zusammenfassung
Aims: Chromogranin A (CgA) has been shown to be a useful marker in the diagnosis of neuroendocrine tumours. Enterochromaffin-like (ECL) cell hyperplasia secondary to hypergastrinemia also leads to an increase of CgA in the blood. It is well established that continuous proton-pump inhibitor (PPI) therapy could significantly increase serum CgA level via hypergastrinemia, but the effect of a single dose of PPI on serum CgA level has not yet been evaluated. Aim: To analyze the acute effect of a single dose of PPI on serum CgA levels during fasting and postprandial, over a period of four hours. Patients and methods:…
