Meta-Analysis of Mortality Patterns in ANCA-Associated Vasculitis Across Regions, Sex, and Subtypes
Young Ho Lee, Gwan Gyu Song · Aktuelle Rheumatologie · 2026 · Heft 02 · S. 106-115
Bibliografische Angaben
Zusammenfassung
Abstract Objectives To evaluate all-cause and cause-specific standardized mortality ratios (SMRs) in patients with ANCA-associated vasculitis (AAV) using meta-analyses stratified by sex, geographic region, and disease subtype. Methods A comprehensive systematic review was conducted using the Medline, Embase, and Web of Sciences databases from inception to April 2025. Meta-analyses were performed to assess all-cause, sex-specific, region-specific, disease-specific, and cause-specific SMRs. Results Twenty-two studies comprising 8,749 AAV patients and 2,503 deaths were included in the meta-analysis. Overall all-cau…