The ZJU Index as a Composite Indicator of Metabolic Burden in Osteoarthritis and Rheumatoid Arthritis: An Internally and Externally Validated Study
Xuanyu Zhang, Yuxuan Liu, Feichao Song, Junfeng Zhang · Aktuelle Rheumatologie · 2026 · Heft 04
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Zusammenfassung
Abstract Background This multi-center study aimed to investigate the association between the ZJU index, a composite indicator of metabolic disturbance, and the prevalence of osteoarthritis (OA) and rheumatoid arthritis (RA). Methods Clinical data from inpatients in an in-hospital cohort and the NHANES 2005–2018 database were analyzed. The association between the ZJU index and the presence of OA and RA was assessed using multivariate logistic regression models adjusted for demographics, comorbidities, and medication use. Z-score transformation of the ZJU index was applied to estimate odds ratios (OR) per 1-standa…