Treatment with standardized mistletoe extract (Viscum album L.) Iscador® as a part of long-term supportive care in patients with primary non-metastatic colorectal carcinoma

Aims: Mistletoe therapy is a frequently used supportive treatment in cancer patients to improve quality of life and baseline therapy induced adverse events. Objectives: To evaluate efficacy and safety of the standardized mistletoe extract Iscador® (ISC) in supportive care of surgically treated patients with primary non-metastatic colorectal carcinoma in comparison with a parallel control group without ISC. Methods: In a multicenter, epidemiological, observational cohort study in Germany and Switzerland, ISC was given in addition to conventional adjuvant chemo- and radiotherapy, and the control was treated with c…