Quantification of muscle tone in patients with REM sleep behavior disorder

Introduction: REM sleep behaviour disorder (RBD) is characterised by excessive tone of the chin muscle and limb movement during sleep. In the past quantification of increased muscle tone in REM sleep has been performed visually using no stringent criteria. The aim of this study was to develop an automatic analysis allowing the quantification of muscle activity and its amplitude for all sleep stages, with a focus on REM sleep in patients with RBD. Methods: 48 patients (27 male, 21 female) with RBD were included in the analysis. 21 had idiopathic RBD, 28 had narcolepsy plus RBD. 25 patients without confirmed sleep…