Intravenous immunoglobulins (IVIG) as long-term therapy in general myasthenia gravis: A case series

Introduction: Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies against acetylcholine receptors at the neuromuscular junction. Steroids and azathioprin are established for long-term immunosuppressive treatment. In cases of failed efficacy other immunosuppressive drugs, like ciclosporine, metho-trexate or mycophenolate can be used. Additionally, IVIG is accepted to be administered in myasthenic crisis or acute exacerbation of motor function without respiratory insufficiency, but not as „add-on“ long-term treatment. Nevertheless, myasthenia gravis symptoms are not always stable under immunos…