Cardiac 31P-MRS compared to echocardiographic findings in patients with hypertensive heart disease without overt systolic dysfunction – preliminary results

Ziele: To evaluate changes in high energy phosphate (HEP) metabolism in patients with hypertension and diastolic dysfunction assessed in electrocardiography and tissue Doppler but with normal LVEF >55%. Methode: 20 Patients (16 men and 4 women, mean age 57±13 years) were studied with phosphorus magnetic resonance spectroscopy and echocardiography. MRS was performed at 1.5 Tesla using an ECG-gated CSI sequence with nuclear Overhauser effect. According to electrocardiographical findings 12 patients were found to have a diastolic dysfunction whereas 8 patients were identified as normal, serving as control group in…