Perfusion Imaging in the Soft Tissues in Patients with Diabetic Foot Syndrome (DFS) – Preliminary Results

Purpose: Reduced arterial perfusion is a major risk in the development of ischemia of the lower extremity with following amputation in patients with diabetic foot syndrome (DFS). Due to neuropathy, early diagnosis and evaluation of existing ischemia is essential to avoid major-amputations. However, standard diagnostic tools to assess perfusion in the foot suffer from reduced penetration or inaccuracy. The aim of this study was to quantitatively measure the perfusion in the foot in patients with DFS using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and Gadofosveset as bloodpool contrast agent.…