Time-of-day variability and circadian rhythms of groß and fine motor skills in patients with acquired brain damage

Introduction: Human skills such as e.g. groß and fine motor skills are influenced by circadian rhythms. During acute therapy and rehabilitation patients with brain damage are faced with massive changes of their daily life routines. Beyond it seems conceivable that brain damage disturbs complex neurotransmitter systems and other neuronal processes that base on the function of the suprachiasmatic nucleus (SCN) controlling the endogenous clock. This study examines patients versus a matched controll group and attempts to identify alterations of groß and fine motor skills depending on the time-of-day and the environm…