Functional and morphometric studies of the olfactory system in patients with idiopathic normal pressure hydrocephalus

Introduction: The most common form of the hydrocephalus in elderly patients is idiopathic normal pressure hydrocephalus (iNPH). Gait disturbance, dementia and incontinence are the leading symptoms in this complex disease. It is difficult to correctly identify those patients, because other disorders are frequently accompanied by similar symptoms. Because of the hypotheses related to possible CSF absorptive pathways through the olfactory pathway, we analyzed the MRI-morphologic characteristics of the olfactory bulb (OB) in patients with iNPH and compared them to healthy controls. Comprehensive assessment of olfact…