Are increased values of blood myoglobin and creatinkinase pathologic?

Introduction: A 30 year old MS patient showing a blood CK value of 6000U/l was admitted for mitoxantron therapy. The further exploration revealed that he had excessively performed fitness exercises at the preceeding days. This observation induced the author to an experiment on his own body. Methods: CK, CKMB, Troponin T and myoglobin were checked in blood plasma before and after long distance runs of 10, 21, 42km and a mountain run over 30.2km. After the latter the values were estimated daily over 6 days. Results: Any Trop T values were normal. CK values (normal ≤190U/l) after the runs were 185, 247, 341 and 410…