Liver transplantation for patients with acute on chronic liver failure: an intention to treat analysis

Acute on chronic liver failure (ACLF), defined as acute deterioration of a patient with compensated liver disease, carries a high risk of mortality mainly due to multi-organ dysfunction. Liver transplantation (LT) is the only curative therapeutic option for these patients. The aim of this study was to determine the efficacy of LT in the treatment of patients with ACLF referred to a tertiary center. Eighty-four consecutive patients with decompensated liver cirrhosis who required intensive monitoring and/or could not be treated outside an intermediate care unit were included in this study. The mean age was 55 year…